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Science Beat

Scientist Creates Alternatives to Chemical Testing on Animals

by Katerina Lorenzatos Makris


A top honor from the Physicians Committee for Responsible Medicine (PCRM) has gone to the head of a group finding alternatives to the use of animals for chemical testing.

Gilman D. Veith, Ph.D., founder and president of the nonprofit International QSAR Foundation to Reduce Animal Testing (IQF), received the Henry J. Heimlich Award for Innovative Medicine at the PCRM’s 25th Anniversary gala on Saturday in West Hollywood.

Speaking before an assembly of PCRM supporters that included numerous Hollywood celebrities, Veith said, “The arts have led the way in creating virtual reality in the movie theatres, but science is on the edge right now and on the verge of creating virtual reality and virtual animals, most of which will be those [species] that are commonly used in animal testing.

“Our QSAR foundation works to create the virtual world of toxicology in animal testing so that we can have safer foods, safer homes, factories, and drugs without killing billions of animals.”


rabbit used in medical research
(Photo - Animal's voice)

“Our QSAR foundation works to create the virtual world of toxicology in animal testing so that we can have safer foods, safer homes, factories, and drugs without killing billions of animals.”

IQF’s work “blends computer science, biology, and chemistry to find correlations between chemical structure and biological effects,” as described in the PCRM event program. “IQF’s vision is to reduce reliance on animal tests without loss of public safety.”

QSARs, short for quantitative structure-activity relationships, function as models to predict the side effects of chemicals, eliminating the need to test on animals.

“Dr. Veith believes that the need for reliable alternatives to animal testing is an important moral animal welfare issue,” according to the PCRM, “but that the need does not stop there.” Other problems include the facts that government authorities only have time to adequately evaluate a small fraction of the animal test data for new chemicals being marketed, and that costs for animal testing are very high and rising.

Veith said he has worked with scientists from over 30 countries in creating a QSAR Application Toolbox. “This is a set of software that can be used by government regulators to screen chemicals,” he explained. “It is held now in the public domain by the Organization of Economic Cooperation and Development in Paris. This is freely available to all governments of the world, all industries of the world, and all researchers, to help them in screening chemicals so that you don’t have to do animal testing.”

“Despite all these huge savings of cost for testing chemicals, industries have been very slow to support this technology for a variety of reasons,” said Veith. “As an advocate for new technology and chemical regulation, the QSAR Foundation’s position is often quite lonely. We are caught between the regulators and the regulated industry. This award just renews our determination to reduce animal testing.”

The award was presented to Veith by the physician for whom it is named, Dr. Henry J. Heimlich, inventor of the world-renown Heimlich Maneuver, a first aid technique credited with saving countless thousands of choking victims.

“I am humbled by this experience,” said Veith. “It’s so exciting to be here at this 25th anniversary gala, and to meet Dr. Heimlich, but also to meet so many people who’ve done so much for medicine. I find this to be a highlight of my career, certainly for accepting his award, and for having it presented by Dr. Heimlich.”

Veith thanked PCRM and  People for the Ethical Treatment of Animals (PETA) for guidance and support, and the European Commission (the executive body of the European Union) for partial funding.

Other recipients of PCRM awards on Saturday were:

BENJAMIN SPOCK AWARD
Baxter D. Montgomery, M.D., F.A.C.C. of the Houston Cardiac Association and HCA Wellness Center
For developing a “nutritional boot camp” to help patients break unhealthy habits, and advocating the power of a plant-based diet

ART OF COMPASSION AWARD
Robert L. “Skip” Trimble, attorney
For his work on behalf of animals, including developing low-cost spay/neuter programs for dogs and cats; performing pro bono legal work for animal groups including the Animal Legal Defense Fund; helping form the animal law section of the State Bar of Texas.

ART OF COMPASSION AWARD
Ellen DeGeneres, Portia De Rossi, Marilu Henner. Alicia Silverstone

Katerina Lorenzatos Makris is the author of 17 novels for publishers including Avon, E.P. Dutton, and Simon & Schuster, and hundreds of articles for publications such as National Geographic Traveler, San Francisco Chronicle, and Veggie Life. She wrote a teleplay for CBS and short fiction for The Bark magazine. With coauthor Shelley Frost, she wrote Your Adopted Dog  (The Lyons Press). Holding a B.A. in Environmental Science Studies and a lifelong interest in animal issues, she spends a lot of her time battling a severe addiction to dogs.



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